The pathology is a diffuse increase in peri inter villous fibrinoid and usually with some intervillous thrombi.
Maternal floor infarction wikipedia.
To understand the lesion the conditions in which perivillous fibrinoid forms must also be understood.
The disorder is somewhat misnamed because it is characterized by heavy deposition of fibrin in the decidua beneath the placenta rather than by arterial occlusion.
This website is intended for pathologists and laboratory personnel but not for patients.
In october shortly after i found out the diagnosis of maternal floor infarction massive perivillous fibrin deposition basically huge clots formed around the villi the little fingerlike placental protusions that delivered nutrients to luke making them unable to function i connected with the folks over at the star legacy foundation the only national u s.
Small placental infarcts especially at the edge of the placental disc are considered to be normal at term large placental infarcts are associated with vascular abnormalities e g.
It is moot whether such a lesion which i will call true maternal floor infarction occurs but the term maternal floor infarction is not usually used in this sense.
A pathologic entity characterised by deposition of fibrinoid material in the maternal surface and intervillous spaces of the placenta and which is associated with significant perinatal morbidity and mortality including stillbirth recurrent pregnancy loss premature delivery intrauterine growth restriction and.
Maternal floor infarction abbreviated mfi is a pathology of the placenta.
Maternal floor infarction mfi is a poorly understood placental lesion reportedly associated with intrauterine growth restriction iugr and recurrence.
Organization dedicated to.
In an attempt to determine the frequency course and outcome of maternal floor infarcts 39 215 placentas and pregnancies were reviewed.
Micrograph of a placental infarct.
A maternal floor infarction then should show fibrin or matrix thickening of the maternal surface with otherwise typical changes of infarction in the villi.
By now everyone agrees that maternal floor infarction is a misnomer at least for most of the cases so labeled.
The disease is characterized by extensive fibrin deposition in the intervillous spaces.
Placenta maternal floor infarction.
It is formally known as placental maternal floor infarction it is also known as massive perivillous fibrin deposition.